Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 7/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486013 | 0.87 | CES1 (0.57) | CES1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11483700 | 0.84 | CES1 (0.53) | CES1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL9860776 | 0.83 | CES1 (0.64) | CES1RAB9ASRCCYP2C19HIF1A | |
| SCHEMBL3266492 | 0.80 | CES1 (0.65) | CES1HPGDSMN1; SMN2SRCALDH1A1 | |
| SCHEMBL7591391 | 0.80 | CES1 (0.56) | CES1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11171387 | 0.79 | CES1 (0.58) | CES1SRCALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3272321 | 0.78 | CES1 (0.57) | CES1RAB9AHPGDSMN1; SMN2KIF11 | |
| SCHEMBL11080785 | 0.78 | CES1 (0.57) | CES1HPGDSMN1; SMN2KIF11SRC | |
| SCHEMBL9065321 | 0.78 | CES1 (0.66) | CES1NPC1SMN1; SMN2SRCCYP2C19 | |
| SCHEMBL36702 | 0.78 | CES1 (0.66) | CES1NPC1SMN1; SMN2SRCCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190602-A | PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |