Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11491253 | 0.89 | XIAP (0.41) | LPAR1LPAR5XIAPDPP4MAPK14 | |
| SCHEMBL11478348 | 0.87 | LPAR1 (0.38) | LPAR1LPAR5XIAPDPP4MAPK14 | |
| SCHEMBL11487885 | 0.85 | PARP10 (0.43) | LPAR1LPAR5MMP14 | |
| SCHEMBL11492433 | 0.84 | LTA4H (0.44) | PPARA | |
| SCHEMBL11480978 | 0.82 | MEN1 (0.39) | LMNAL3MBTL1PPARA | |
| SCHEMBL11479623 | 0.81 | XIAP (0.43) | LPAR1LPAR5XIAPMAPK14AR | |
| SCHEMBL11483248 | 0.80 | NPC1 (0.38) | MAPK14PPARA | |
| SCHEMBL11485286 | 0.78 | AR (0.41) | LPAR1LPAR5XIAPDPP4MAPK14 | |
| SCHEMBL11477245 | 0.77 | HSPB1 (0.43) | MAPK14LMNAARL3MBTL1 | |
| SCHEMBL11480174 | 0.77 | MAPT (0.38) | MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4196215-A | Alkyne compounds and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4115456-A | Alkyne compounds and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-19 | — | — | US | disclosed |