Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711653 | 0.91 | HRH3 (0.43) | MAPTADORA3RECQLHRH3 | |
| SCHEMBL11491061 | 0.90 | MAPT (0.39) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11708850 | 0.90 | MAPT (0.47) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11483893 | 0.88 | L3MBTL1 (0.47) | TSHRMAPTALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL11608602 | 0.88 | TSHR (0.37) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11706948 | 0.88 | ALDH1A1 (0.39) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11488469 | 0.88 | GPR119 (0.39) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11484070 | 0.88 | ALDH1A1 (0.39) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11710277 | 0.88 | TSHR (0.37) | TSHRMAPTADORA3RECQLGABRA1 | |
| SCHEMBL11487657 | 0.87 | TSHR (0.36) | TSHRMAPTADORA3RECQLGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220646-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, HYPNOTIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1980-09-02 | — | — | US | disclosed |