SCHEMBL1148637

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14218367	0.90	ALDH1A1 (0.36)	HSP90AA1HSP90AB1POLBALDH1A1TSHR
	SCHEMBL1148698	0.89	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ALDH1A1TSHRMAPT
	SCHEMBL1148726	0.85	ALDH1A1 (0.42)	HSP90AA1HSP90AB1SMN1; SMN2ALDH1A1TSHR
	SCHEMBL4664286	0.84	ESR1 (0.34)	HSP90AA1HSP90AB1SMN1; SMN2ALDH1A1TSHR
	SCHEMBL16604235	0.84	HSP90AA1 (0.59)	HSP90AA1HSP90AB1
	SCHEMBL14453299	0.83	MEN1 (0.36)	HSP90AA1HSP90AB1POLBALDH1A1LMNA
	SCHEMBL13983495	0.79	HSP90AA1 (0.33)	HSP90AA1HSP90AB1POLBALDH1A1LMNA
	SCHEMBL1147910	0.79	HSP90AA1 (0.36)	HSP90AA1HSP90AB1MAPTESR1
	SCHEMBL1148574	0.79	HSP90AA1 (0.38)	HSP90AA1HSP90AB1ALDH1A1TSHRLMNA
	SCHEMBL12046359	0.79	KDM4E (0.41)	HSP90AA1HSP90AB1SMN1; SMN2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.