Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148637 | 0.90 | HSP90AA1 (0.40) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL14453299 | 0.84 | MEN1 (0.36) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL14218203 | 0.79 | LMNA (0.31) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL4664286 | 0.79 | ESR1 (0.34) | ALDH1A1MEN1KMT2ANPC1LMNA | |
| SCHEMBL1148698 | 0.79 | HSP90AA1 (0.50) | ALDH1A1MEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL1148558 | 0.77 | HPGD (0.35) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL1148484 | 0.77 | LMNA (0.36) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL1147921 | 0.77 | LMNA (0.36) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL1148726 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ANPSR1HPGD | |
| SCHEMBL1148522 | 0.76 | LMNA (0.35) | ALDH1A1MEN1KMT2APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051416-A2 | COMPOUNDS THAT INHIBIT THE ACTIVITY OF HSP90 FOR TREATING INFECTIONS | SYNTA PHARMACEUTICALS CORP. (US) | 2008-05-02 | — | — | WO | disclosed |