Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201507 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL11836641 | 0.79 | ALDH1A1 (0.42) | ALDH1A1NPSR1CRHBPCRHR2KMT2A | |
| SCHEMBL11828982 | 0.79 | ALDH1A1 (0.36) | ALDH1A1NPSR1CRHBPCRHR2 | |
| SCHEMBL11849277 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPSR1CRHBPCRHR2S100A4 | |
| SCHEMBL11486146 | 0.76 | CA12 (0.40) | — | |
| SCHEMBL11833969 | 0.75 | — | — | |
| SCHEMBL11844709 | 0.70 | ALDH1A1 (0.38) | ALDH1A1NPSR1CRHBPCRHR2L3MBTL1 | |
| SCHEMBL11857335 | 0.70 | ALDH1A1 (0.38) | ALDH1A1NPSR1CRHBPCRHR2 | |
| SCHEMBL11260968 | 0.67 | RECQL (0.34) | — | |
| SCHEMBL12910406 | 0.66 | PTPN22 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220646-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, HYPNOTIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1980-09-02 | — | — | US | disclosed |
| US-3966931-A | TRANQUILIZERS, ANTICONVULSANTS, HYPNOSIS | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3948917-A | TRANQUILIZERS, ANTICONVULSANTS, DECONTRACTURANTS, HYPNOSIS | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |