SCHEMBL1148699

SCHEMBL1148699

Nc1ncccc1-c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 4/20 0.66
MKNK1 Q9BUB5 2/20 0.59
MKNK2 Q9HBH9 2/20 0.59
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CDK1 P06493 1/20 0.47
CDK2 P24941 1/20 0.47
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
SMARCA2 P51531 2/20 0.45
SMARCA4 P51532 2/20 0.45
PBRM1 Q86U86 2/20 0.45
TDO2 P48775 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
USP7 Q93009 1/20 0.44
CSF1R P07333 1/20 0.44
FGFR1 P11362 1/20 0.44
PDGFRA P16234 1/20 0.44
LTK P29376 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623411 0.96 MAP4K4 (0.61) MAP4K4MKNK1MKNK2ALDH1A1HSD17B10
SCHEMBL18188070 0.86 MAP4K4 (0.71) MAP4K4MKNK1MKNK2CDK1CDK2
SCHEMBL11127668 0.84 MAP4K4 (0.58) MAP4K4MKNK1MKNK2CDK1CDK2
SCHEMBL29442167 0.84 MAP4K4 (0.58) MAP4K4MKNK1MKNK2CDK1CDK2
Trifluoroacetic Acid SCHEMBL28137339 0.84 MKNK1 (0.58) MAP4K4MKNK1MKNK2NAPRTUSP7
SCHEMBL625021 0.83 MKNK1 (0.53) MAP4K4MKNK1MKNK2ALDH1A1CDK1
SCHEMBL625020 0.83 MKNK1 (0.53) MAP4K4MKNK1MKNK2ALDH1A1CDK1
SCHEMBL623507 0.83 MKNK1 (0.53) MAP4K4MKNK1MKNK2KDRTNK2
SCHEMBL624380 0.83 MAP4K4 (0.57) MAP4K4MKNK1MKNK2NOS3NOS1
SCHEMBL625444 0.83 MAP4K4 (0.57) MAP4K4MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250185655-A1 PHEROMONE COMPOSITIONS, METHODS OF MAKING, AND THEIR USES PHERONYM INC. (US) 2025-06-12 US claimed
CN-118555910-A Fungicidal mixtures comprising a combination containing phthalimide fungicides 安道麦马克西姆有限公司 2024-08-27 CN claimed
EP-4408173-A1 PHEROMONE COMPOSITIONS, METHODS OF MAKING, AND THEIR USES Pheronym Inc. (US) 2024-08-07 EP claimed
WO-2023055588-A1 PHEROMONE COMPOSITIONS, METHODS OF MAKING, AND THEIR USES PHERONYM, INC. (US) 2023-04-06 WO claimed
CN-109651366-A The preparation method of nitrogen-containing heterocycle hexafluoro borate 河南师范大学 2019-04-19 CN claimed
CN-108484656-A A kind of preparation method of four-coordination triarylboron 华侨大学 2018-09-04 CN claimed
US-20170049103-A1 METHOD FOR BREAKING DORMANCY IN DECIDUOUS TREES TAPAZOL CHEMICAL WORKS LTD. (IL) 2017-02-23 US claimed
US-9445599-B2 Lignin-based microparticles for the controlled release of agricultural actives MONSANTO TECHNOLOGY LLC (US) 2016-09-20 US claimed
WO-2015166499-A1 METHOD FOR BREAKING DORMANCY IN DECIDUOUS TREES TAPAZOL CHEMICAL WORKS LTD. (IL) 2015-11-05 WO claimed
CN-102548418-A Plant pathogen inhibitor combinations and methods of use MARRONE BIO INNOVATIONS INC 2012-07-04 CN claimed
US-20110028500-A1 PLANT PATHOGEN INHIBITOR COMBINATIONS AND METHODS OF USE MARRONE BIO INNOVATIONS, INC. (US) 2011-02-03 US claimed
WO-2011014596-A2 PLANT PATHOGEN INHIBITOR COMBINATIONS AND METHODS OF USE MARRONE BIO INNOVATIONS, INC. (US) 2011-02-03 WO claimed
US-7771749-B2 Lignin-based microparticles for the controlled release of agricultural actives MONSANTO TECHNOLOGY LLC (US) 2010-08-10 US claimed
WO-2010077992-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS AMGEN INC. (US) 2010-07-08 WO claimed
US-20080234129-A1 Controlled release; soluble in methyl chloride; desolventizing MONSANTO TECHNOLOGY, LLC 2008-09-25 US claimed
CN-1845734-A Benzimidazole derivatives and their use as protein kinases inhibitors ASTEX THERAPEUTICS LTD (GB) 2006-10-11 CN claimed
EP-1404176-B1 LIGNIN MICROPARTICLES FOR CONTROLLED RELEASE OF AGRICULTURAL ACTIVES MONSANTO TECHNOLOGY LLC (US) 2006-02-22 EP claimed
EP-1404176-A1 LIGNIN MICROPARTICLES FOR CONTROLLED RELEASE OF AGRICULTURAL ACTIVES Monsanto Technology LLC (US) 2004-04-07 EP claimed
WO-2003005816-A1 LIGNIN MICROPARTICLES FOR CONTROLLED RELEASE OF AGRICULTURAL ACTIVES MONSANTO TECHNOLOGY, LLC (US) 2003-01-23 WO claimed
US-20030013612-A1 Lignin-based microparticles for the controlled release of agricultural actives MONSANTO TECHNOLOGY, L.L.C. (US) 2003-01-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250185655-A1 PHEROMONE COMPOSITIONS, METHODS OF MAKING, AND THEIR USES PTMS, NGLY1, HUNK MAP4K4 3603/4885MKNK1 424/4885MKNK2 449/4885
US-20110028500-A1 PLANT PATHOGEN INHIBITOR COMBINATIONS AND METHODS OF USE BAK1, BROX, ERG28 MAP4K4 2784/4885MKNK1 347/4885MKNK2 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.