Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.71 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623411 | 0.86 | MAP4K4 (0.61) | MAP4K4MKNK1MKNK2USP7CDK1 | |
| SCHEMBL1148699 | 0.86 | MAP4K4 (0.66) | MAP4K4MKNK1MKNK2USP7CDK1 | |
| SCHEMBL4582777 | 0.80 | MAP4K4 (0.69) | MAP4K4MKNK1MKNK2CDK1CDK2 | |
| SCHEMBL4582784 | 0.80 | MAP4K4 (0.69) | MAP4K4MKNK1MKNK2MAP2K1NOS3 | |
| SCHEMBL12100759 | 0.80 | MAP4K4 (0.46) | MAP4K4MAOAMAP3K8USP7MAPK1 | |
| SCHEMBL31145789 | 0.78 | MAP3K8 (0.49) | MAP4K4MKNK1MKNK2MAP3K8MAPK1 | |
| SCHEMBL625444 | 0.78 | MAP4K4 (0.57) | MAP4K4MKNK1MKNK2FEN1 | |
| SCHEMBL623802 | 0.78 | FEN1 (0.52) | MAP4K4MKNK1MKNK2FEN1 | |
| SCHEMBL624380 | 0.78 | MAP4K4 (0.57) | MAP4K4MKNK1MKNK2USP7NOS3 | |
| SCHEMBL28827012 | 0.78 | MAP4K4 (0.43) | MAP4K4MAOAMAPK1PIK3CAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10700308-B2 | Aromatic amine compound, light-emitting element materials and light-emitting element | TORAY INDUSTRIES, INC. (JP) | 2020-06-30 | — | — | US | disclosed |
| EP-3088403-B1 | AROMATIC AMINE COMPOUND FOR LIGHT-EMITTING ELEMENT | TORAY INDUSTRIES (JP) | 2020-02-12 | — | — | EP | disclosed |
| US-20160322606-A1 | AROMATIC AMINE COMPOUND, LIGHT-EMITTING ELEMENT MATERIALS AND LIGHT-EMITTING ELEMENT | TORAY INDUSTRIES, INC. (JP) | 2016-11-03 | — | — | US | disclosed |
| EP-3088403-A1 | AROMATIC AMINE COMPOUND, LIGHT-EMITTING ELEMENT MATERIALS AND LIGHT-EMITTING ELEMENT | Toray Industries, Inc. (JP) | 2016-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10700308-B2 | Aromatic amine compound, light-emitting element materials and light-emitting element | TYR, LAMP1, MAP1LC3B | MAP4K4 1862/4885MKNK1 3587/4885MKNK2 3595/4885 |
| US-20160322606-A1 | AROMATIC AMINE COMPOUND, LIGHT-EMITTING ELEMENT MATERIALS AND LIGHT-EMITTING ELEMENT | TYR, LAMP1, MAP1LC3B | MAP4K4 1862/4885MKNK1 3587/4885MKNK2 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.