SCHEMBL11487151

SCHEMBL11487151

CC(CCN1CCCCC1)c1ccc(-c2ccc(F)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.54
SCN5A Q14524 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11494698 1.00 ACHE (0.54) ACHESCN5A
SCHEMBL11496323 0.98 ACHE (0.53) ACHESCN5A
SCHEMBL11492745 0.91 SCN5A (0.54) ACHESCN5A
SCHEMBL11488050 0.88 SLC6A2 (0.47)
SCHEMBL11487600 0.87 LTA4H (0.57) ACHESCN5A
SCHEMBL11487124 0.87 LTA4H (0.57) ACHESCN5A
SCHEMBL11492685 0.87 SLC6A2 (0.47)
SCHEMBL11493097 0.86
SCHEMBL29767808 0.86
SCHEMBL11487957 0.85 ACHE (0.57) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4239759-A Morpholino containing compounds, compositions and use thereof MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-12-16 US disclosed
US-4110447-A Anti-inflammatory (halo-4-biphenylyl)-alkanolamines MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1978-08-29 US disclosed