Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487600 | 1.00 | LTA4H (0.57) | LTA4HACHEALDH1A1HRH3PSMB1 | |
| SCHEMBL11488829 | 0.99 | LTA4H (0.58) | LTA4HACHEALDH1A1PSMB1PSMB5 | |
| SCHEMBL11487807 | 0.87 | HRH3 (0.57) | LTA4HALDH1A1HRH3PSMB1PSMB5 | |
| SCHEMBL11487410 | 0.87 | HRH3 (0.57) | LTA4HALDH1A1HRH3PSMB1PSMB5 | |
| SCHEMBL11494698 | 0.87 | ACHE (0.54) | ACHESCN5A | |
| SCHEMBL11487151 | 0.87 | ACHE (0.54) | ACHESCN5A | |
| SCHEMBL11485735 | 0.86 | ACHE (0.53) | LTA4HACHEALDH1A1SLC6A4 | |
| SCHEMBL11489240 | 0.86 | SIGMAR1 (0.54) | LTA4HSLC6A4 | |
| SCHEMBL11489075 | 0.86 | ALDH1A1 (0.43) | LTA4HACHEALDH1A1HRH3PSMB1 | |
| SCHEMBL11496154 | 0.86 | ALDH1A1 (0.43) | LTA4HACHEALDH1A1HRH3PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |