Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496014 | 0.83 | LMNA (0.43) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11488655 | 0.82 | L3MBTL1 (0.41) | MAPTMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL11495649 | 0.81 | LMNA (0.43) | CA2LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL5068100 | 0.78 | LMNA (0.52) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11487188 | 0.78 | AKR1B1 (0.46) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11487927 | 0.78 | CA2 (0.49) | CA2LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL1177658 | 0.76 | NSD2 (0.57) | CA2LMNAALDH1A1KDM4EGAA | |
| SCHEMBL11493640 | 0.76 | MAPT (0.39) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL11486484 | 0.76 | CA2 (0.47) | CA2LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL11489027 | 0.76 | CA2 (0.47) | CA2LMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |