Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.58 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.57 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.57 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.57 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.57 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.57 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.57 |
| ▸ | CASR | P41180 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27063852 | 0.86 | SMN1; SMN2 (0.63) | KLK7HTTGPR88RAB9ANPC1 | |
| SCHEMBL14629743 | 0.86 | RAB9A (0.59) | HTTRAB9ANPC1PSEN1PSEN2 | |
| SCHEMBL7748974 | 0.85 | POLB (0.66) | KLK7HTTL3MBTL1PSEN1PSEN2 | |
| SCHEMBL17365594 | 0.85 | POLB (0.66) | KLK7HTTL3MBTL1PSEN1PSEN2 | |
| SCHEMBL28812721 | 0.84 | KLK7 (0.64) | KLK7HTTL3MBTL1RAB9ANPC1 | |
| SCHEMBL6718171 | 0.83 | KLK7 (0.63) | KLK7HTTL3MBTL1RAB9ANPC1 | |
| SCHEMBL14599718 | 0.82 | MAPT (0.72) | HTTRAB9ANPC1PSEN1PSEN2 | |
| SCHEMBL11487355 | 0.82 | MAPT (0.72) | HTTRAB9ANPC1PSEN1PSEN2 | |
| SCHEMBL6715776 | 0.82 | KLK7 (0.61) | KLK7HTTL3MBTL1RAB9ANPC1 | |
| SCHEMBL27291253 | 0.81 | MEN1 (0.71) | L3MBTL1MEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |