Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11432679 | 0.99 | PTGS2 (0.43) | PTGS2MAOBACHEPSEN1PSEN2 | |
| SCHEMBL11431651 | 0.85 | PSEN1 (0.53) | PTGS2MAOBPSEN1PSEN2APH1B | |
| SCHEMBL11421999 | 0.79 | TSHR (0.52) | MAOBACHECYP1A2CYP3A4CYP2C19 | |
| Furcloprofen SCHEMBL30608641 | 0.79 | PTGS2 (0.56) | PTGS2PSEN1PSEN2APH1BNCSTN | |
| Furcloprofen SCHEMBL287046 | 0.79 | PTGS2 (0.56) | PTGS2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11246813 | 0.78 | PTGS2 (0.46) | PTGS2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL11421996 | 0.78 | TSHR (0.54) | MAOBACHECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11431601 | 0.78 | AHR (0.46) | PTGS2MAOBAHRTTRMEN1 | |
| Methane SCHEMBL11432684 | 0.77 | TSHR (0.53) | MAOBACHECYP1A2CYP3A4CYP2C19 | |
| Methane SCHEMBL11431842 | 0.77 | TSHR (0.52) | MAOBACHECYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222944-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-09-16 | — | — | US | disclosed |