Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | C5 | P01031 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furcloprofen SCHEMBL287046 | 1.00 | PTGS2 (0.56) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11431601 | 0.88 | AHR (0.46) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11423247 | 0.84 | CSNK2A2 (0.43) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11422966 | 0.83 | AKR1C3 (0.43) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL11431651 | 0.83 | PSEN1 (0.53) | PTGS2TTRAHRPSEN1PSEN2 | |
| SCHEMBL11434643 | 0.82 | AKR1B1 (0.55) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL11485002 | 0.80 | MMP12 (0.52) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL11431221 | 0.79 | AHR (0.49) | TTRAHRPSEN1PSEN2APH1B | |
| SCHEMBL11487556 | 0.79 | PTGS2 (0.44) | PTGS2MEN1ABCC4C5MAPT | |
| Hydrochloric Acid SCHEMBL11432679 | 0.78 | PTGS2 (0.43) | PTGS2MEN1ABCC4C5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294652-A1 | IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS | AMGEN K-A, INC. | 2024-09-05 | — | — | US | disclosed |
| US-11858999-B2 | IL-17 receptor A antigen binding proteins | AMGEN K-A, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| CN-116887880-A | Balloon catheter and method of use | 开金血管公司 | 2023-10-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858999-B2 | IL-17 receptor A antigen binding proteins | IL17A, IL23R, IL15RA | PTGS2 3854/4885MEN1 4496/4885ABCC4 4121/4885 |
| US-20240294652-A1 | IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS | IL17A, IL23R, IL15RA | PTGS2 3854/4885MEN1 4496/4885ABCC4 4121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.