Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | C5 | P01031 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furcloprofen SCHEMBL30608641 | 1.00 | PTGS2 (0.56) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11431601 | 0.88 | AHR (0.46) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11423247 | 0.84 | CSNK2A2 (0.43) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11422966 | 0.83 | AKR1C3 (0.43) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL11431651 | 0.83 | PSEN1 (0.53) | PTGS2TTRAHRPSEN1PSEN2 | |
| SCHEMBL11434643 | 0.82 | AKR1B1 (0.55) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL11485002 | 0.80 | MMP12 (0.52) | PTGS2MEN1MAPTPTGS1KMT2A | |
| SCHEMBL11431221 | 0.79 | AHR (0.49) | TTRAHRPSEN1PSEN2APH1B | |
| SCHEMBL11487556 | 0.79 | PTGS2 (0.44) | PTGS2MEN1ABCC4C5MAPT | |
| Hydrochloric Acid SCHEMBL11432679 | 0.78 | PTGS2 (0.43) | PTGS2MEN1ABCC4C5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | claimed |
| US-20110212173-A1 | Controlled Release Treatment of Depression | e-Therapeutics Ple (GB) | 2011-09-01 | — | — | US | claimed |
| EP-2315585-A1 | CONTROLLED RELEASE TREATMENT OF DEPRESSION | E-Therapeutics plc (GB) | 2011-05-04 | — | — | EP | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101801361-A | Treatment of depression | THERAPEUTICS LTD E | 2010-08-11 | — | — | CN | claimed |
| WO-2010004256-A1 | CONTROLLED RELEASE TREATMENT OF DEPRESSION | E-THERAPEUTICS PLC (GB) | 2010-01-14 | — | — | WO | claimed |
| EP-2014282-A2 | Treatment of depression | E-Therapeutics plc (GB) | 2009-01-14 | — | — | EP | claimed |
| US-20090005443-A1 | Treatment of Depression | E-THERAPEUTICS LIMITED (GB) | 2009-01-01 | — | — | US | claimed |
| WO-2009001040-A2 | TREATMENT OF DEPRESSION | E-THERAPEUTICS PLC (GB) | 2008-12-31 | — | — | WO | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| CN-101237857-A | Compositions and methods using microspheres and non-ionic contrast agents | BIOSPHERE MEDICAL S A (FR) | 2008-08-06 | — | — | CN | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-4855446-A | Process for the resolution of racemates using lactone esters | THE SHERWIN WILLIAMS COMPANY (US) | 1989-08-08 | — | — | US | claimed |
| EP-0060445-B1 | PROCESS FOR THE RESOLUTION OF RACEMATES AND LACTONE ESTERS USED IN SAID PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-08-01 | — | — | EP | claimed |
| EP-0060445-A1 | Process for the resolution of racemates and lactone esters used in said process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-22 | — | — | EP | claimed |
| US-4022805-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1977-05-10 | — | — | US | claimed |