Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496251 | 0.88 | KMT2A (0.50) | ALDH1A1MEN1KMT2ANCOA1NCOA3 | |
| SCHEMBL11487270 | 0.87 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ANCOA1NCOA3 | |
| SCHEMBL11487623 | 0.86 | LTA4H (0.50) | ALDH1A1TSHRHTTKDM4ETDP1 | |
| SCHEMBL11496126 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ANCOA1NCOA3 | |
| SCHEMBL11486730 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL11495695 | 0.75 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATSHRHTT | |
| SCHEMBL11486521 | 0.75 | KMT2A (0.47) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL11494367 | 0.75 | MEN1 (0.48) | ALDH1A1MEN1KMT2ANCOA3HPGD | |
| SCHEMBL11487323 | 0.75 | LTA4H (0.56) | ALDH1A1MEN1KMT2ATSHRHTT | |
| SCHEMBL11492547 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |