Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252918 | 0.89 | — | — | |
| SCHEMBL11260349 | 0.86 | MAOA (0.32) | MAOAMAOBFAAH | |
| SCHEMBL11492319 | 0.84 | ADRB2 (0.34) | MAOAMAOBALDH1A1MAPT | |
| SCHEMBL11488815 | 0.84 | — | — | |
| SCHEMBL11252762 | 0.83 | CSNK2A2 (0.34) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11255580 | 0.82 | MEN1 (0.30) | MAPT | |
| SCHEMBL11254004 | 0.81 | MAOA (0.33) | MAOAMAOBALDH1A1MAPTCSNK2A2 | |
| SCHEMBL11486194 | 0.80 | MAOA (0.33) | MAOAMAOBALDH1A1MAPTCSNK2A2 | |
| SCHEMBL11487777 | 0.77 | MAOB (0.39) | MAOAMAOBALDH1A1MAPTCSNK2A2 | |
| SCHEMBL11489174 | 0.75 | CSNK2A2 (0.35) | MAOAMAOBALDH1A1MAPTCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206225-A | ANALGESICS | PFIZER INC. (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0009386-A1 | 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-04-02 | — | — | EP | disclosed |