Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 7/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252762 | 0.89 | CSNK2A2 (0.34) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11487635 | 0.81 | MAOA (0.33) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11492319 | 0.80 | ADRB2 (0.34) | MAOAMAOBALDH1A1MAPT | |
| SCHEMBL11489174 | 0.80 | CSNK2A2 (0.35) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11486138 | 0.79 | FAAH (0.35) | FAAHMGLLALDH1A1 | |
| SCHEMBL11493781 | 0.74 | OPRM1 (0.31) | — | |
| SCHEMBL11487777 | 0.74 | MAOB (0.39) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11493129 | 0.74 | FAAH (0.31) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11486194 | 0.70 | MAOA (0.33) | MAOAMAOBCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11252918 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009386-B1 | 2,10-DISUBSTITUTED DIBENZO(B,D)PYRANS AND BENZO(C)QUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4206225-A | ANALGESICS | PFIZER INC. (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0009386-A1 | 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-04-02 | — | — | EP | disclosed |