Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 9/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695327 | 1.00 | MMP1 (0.38) | MMP1MMP9MMP13FAAHEPHX2 | |
| SCHEMBL3857912 | 0.98 | MMP1 (0.36) | MMP1MMP9MMP13FAAHEPHX2 | |
| SCHEMBL6623865 | 0.93 | PSIP1 (0.35) | SOAT1 | |
| SCHEMBL3540671 | 0.86 | PSIP1 (0.38) | — | |
| SCHEMBL11420929 | 0.81 | CNR2 (0.44) | — | |
| SCHEMBL11426081 | 0.81 | CNR2 (0.44) | — | |
| SCHEMBL159759 | 0.80 | PSIP1 (0.46) | FAAH | |
| SCHEMBL9769421 | 0.80 | TDP1 (0.41) | THRATHRB | |
| SCHEMBL10613927 | 0.78 | CNR2 (0.45) | — | |
| SCHEMBL9322186 | 0.78 | THRB (0.41) | SOAT1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204867-A | THIAZOLE OR IMIDAZOLE FOUR EQUILVALENT COUPLERS | AGFA-GEVAERT, A.G. (DE) | 1980-05-27 | — | — | US | disclosed |
| US-4183752-A | DEVELOPMENT INHIBITOR RELEASING THIOETHERS | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |