Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171146 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDF7F3AHR | |
| SCHEMBL1192946 | 0.79 | F7 (0.47) | ALDH1A1PSMB8HPGDF7F3 | |
| SCHEMBL4794109 | 0.76 | F7 (0.44) | ALDH1A1PSMB8HPGDF7F3 | |
| SCHEMBL9305046 | 0.76 | F7 (0.44) | ALDH1A1PSMB8HPGDF7F3 | |
| SCHEMBL216615 | 0.76 | HTR3E (0.72) | ALDH1A1F7F3AHRLTA4H | |
| SCHEMBL482225 | 0.76 | F7 (0.44) | ALDH1A1PSMB8HPGDF7F3 | |
| SCHEMBL4441068 | 0.76 | KMT2A (0.51) | ALDH1A1PSMB8HPGDHSD17B10POLB | |
| SCHEMBL2884818 | 0.76 | ALDH1A1 (0.72) | ALDH1A1HPGDF7F3AHR | |
| SCHEMBL9306284 | 0.76 | F7 (0.44) | ALDH1A1PSMB8HPGDF7F3 | |
| Bromide SCHEMBL215261 | 0.74 | HTR3E (0.70) | ALDH1A1F7F3AHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234578-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |