SCHEMBL9305046

SCHEMBL9305046

Clc1ccc2[nH]c(Br)nc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 2/20 0.44
F3 P13726 2/20 0.44
AHR P35869 2/20 0.44
LTA4H P09960 1/20 0.44
NR4A2 P43354 1/20 0.44
HRH4 Q9H3N8 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR3A P46098 1/20 0.43
BACE1 P56817 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
NOS1 P29475 1/20 0.41
DYRK1A Q13627 1/20 0.41
F11 P03951 1/20 0.40
PIK3CG P48736 1/20 0.40
HPGD P15428 3/20 0.40
PSMB8 P28062 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305060 0.84 ALDH1A1 (0.61) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL1192946 0.79 F7 (0.47) F7F3AHRLTA4HNR4A2
SCHEMBL4483413 0.79 NOS1 (0.44) AHRNR4A2ALDH1A1BACE1NOS1
SCHEMBL1171146 0.79 ALDH1A1 (0.53) F7F3AHRLTA4HNR4A2
SCHEMBL482225 0.76 F7 (0.44) F7F3AHRLTA4HNR4A2
SCHEMBL4794109 0.76 F7 (0.44) F7F3AHRLTA4HNR4A2
SCHEMBL216615 0.76 HTR3E (0.72) F7F3AHRLTA4HNR4A2
SCHEMBL22955322 0.76 ALPL (0.40) AHRALDH1A1HPGDSMN1; SMN2TDP1
SCHEMBL2884818 0.76 ALDH1A1 (0.72) F7F3AHRLTA4HNR4A2
SCHEMBL29824694 0.76 ALPL (0.40) AHRALDH1A1HPGDSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2026-05-07 US disclosed
EP-4710922-A2 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2026-03-18 EP disclosed
EP-4003337-B1 ARYL HYDROCARBON RECEPTOR ACTIVATORS UNIV OREGON STATE (US) 2026-03-11 EP disclosed
US-12473262-B2 Aryl hydrocarbon receptor activators OREGON STATE UNIVERSITY (US) 2025-11-18 US disclosed
US-20220281824-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2022-09-08 US disclosed
EP-4003337-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2022-06-01 EP disclosed
WO-2021022061-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2021-02-04 WO disclosed
US-10882850-B2 Organic compound with triazine and benzimidazole as core and application thereof in organic electroluminescent device JIANGSU SUNERA TECHNOLOGY CO., LTD (CN) 2021-01-05 US disclosed
US-10882850-B2 Organic compound with triazine and benzimidazole as core and application thereof in organic electroluminescent device JIANGSU SUNERA TECHNOLOGY CO., LTD (CN) 2021-01-05 US disclosed
US-20190071430-A1 Organic Compound with Triazine and Benzimidazole as Core and Application thereof in Organic Electroluminescent Device Jiangsu Sunera Technology Co.,Ltd (CN) 2019-03-07 US disclosed
US-9643933-B2 Compounds useful as antibiotic tolerance inhibitors THE GENERAL HOSPITAL CORPORATION (US) 2017-05-09 US disclosed
US-20160052890-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2016-02-25 US disclosed
US-20160052890-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2016-02-25 US disclosed
US-20160052890-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2016-02-25 US disclosed
US-20140378525-A1 MATERIALS AND METHODS FOR TREATING PTEN MUTATED OR DEFICIENT CANCER THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2014-12-25 US disclosed
WO-2014176258-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2014-10-30 WO disclosed
WO-2014176258-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2014-10-30 WO disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0129506-A2 Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids CIBA-GEIGY AG (CH) 1984-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281824-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR0B1 F7 4859/4885F3 3054/4885AHR 1/4885
US-20190071430-A1 Organic Compound with Triazine and Benzimidazole as Core and Application thereof in Organic Electroluminescent Device BRD4, BRD7, BRD3 F7 1461/4885F3 1530/4885AHR 13/4885
US-20140378525-A1 MATERIALS AND METHODS FOR TREATING PTEN MUTATED OR DEFICIENT CANCER BUB1B, TTK, BUB1 F7 4214/4885F3 4254/4885AHR 4807/4885
US-10882850-B2 Organic compound with triazine and benzimidazole as core and application thereof in organic electroluminescent device BRD4, BRD7, BRD3 F7 1461/4885F3 1530/4885AHR 13/4885
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR1H2 F7 2352/4885F3 1288/4885AHR 1/4885
US-12473262-B2 Aryl hydrocarbon receptor activators AHR, ARNT, NR0B1 F7 4859/4885F3 3054/4885AHR 1/4885
US-20160052890-A1 COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS CFTR, SLC11A2, MRPS18A F7 102/4885F3 90/4885AHR 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.