Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4739389 | 0.98 | HTR2A (0.42) | HTR2AHTR2CCHRM2CHRM4CHRM5 | |
| SCHEMBL5179163 | 0.78 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28312964 | 0.76 | TDP1 (0.40) | HTR2AHTR2CMEN1 | |
| SCHEMBL29674239 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL22541598 | 0.75 | HTR2A (0.47) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL24710630 | 0.75 | MAOB (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL327743 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL11488652 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL29674233 | 0.75 | HTR2A (0.47) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL17114772 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | claimed |
| CN-105372367-B | A kind of detection method of lamb's-quarters beans extract | 苏州大学 | 2017-06-06 | — | — | CN | disclosed |
| CN-1549716-B | 3-substituted 6, 7-dihydroxytetrahydroisoquinoline derivatives for use in antibacterial agents | ARPIDA AG | 2010-05-26 | — | — | CN | disclosed |
| EP-1045837-B1 | MONOMERIC AND DIMERIC ARYLISOQUINOLINE ALKALOIDS AND DERIVATIVES THEREOF | US GOV HEALTH & HUMAN SERV (US) | 2007-03-14 | — | — | EP | disclosed |
| CN-1549716-A | 3-substituted 6, 7-dihydroxytetrahydroisoquinoline derivatives for use in antibacterial agents | ��Ƥ�¹ɷ�����˾ | 2004-11-24 | — | — | CN | disclosed |
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| US-6331630-B1 | Dimeric arylisoquinoline alkaloids and derivatives thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-12-18 | — | — | US | disclosed |
| US-6140339-A | Monomeric and dimeric arylisoquinoline alkaloids and derivatives thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1045837-A1 | MONOMERIC AND DIMERIC ARYLISOQUINOLINE ALKALOIDS AND DERIVATIVES THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999033811-A1 | MONOMERIC AND DIMERIC ARYLISOQUINOLINE ALKALOIDS AND DERIVATIVES THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, R EPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-07-08 | — | — | WO | disclosed |
| EP-0210828-A2 | Tetrahydroisoquinoline derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITHKLINE BEECHAM CORPORATION (US) | 1987-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | HTR2A 855/4885HTR2C 1349/4885CHRM2 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.