Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LIPA | P38571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496676 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAGAACYP1A2 | |
| SCHEMBL28585644 | 0.88 | GLO1 (0.44) | ALDH1A1LMNAGAACYP2C19GLO1 | |
| SCHEMBL11467396 | 0.88 | GLO1 (0.34) | ALDH1A1KDM4EGAAGLO1MAPT | |
| SCHEMBL11467395 | 0.88 | GLO1 (0.34) | ALDH1A1KDM4EGAAGLO1MAPT | |
| SCHEMBL13966483 | 0.86 | GLO1 (0.35) | ALDH1A1LMNAGAACYP2C19GLO1 | |
| SCHEMBL25563386 | 0.82 | GLO1 (0.41) | ALDH1A1LMNAGAACYP2C19GLO1 | |
| SCHEMBL632279 | 0.82 | GLO1 (0.41) | ALDH1A1LMNAGAACYP2C19GLO1 | |
| SCHEMBL22993864 | 0.80 | GLO1 (0.40) | ALDH1A1LMNAGAAGLO1MAPT | |
| SCHEMBL29117593 | 0.80 | GLO1 (0.40) | ALDH1A1LMNAGAAGLO1MAPT | |
| SCHEMBL2987392 | 0.80 | GLO1 (0.40) | ALDH1A1LMNAGAAGLO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241058-A | INSECTICIDES, MITICIDES, SYSTEMIC | HOFFMANN-LA ROCHE INC. (US) | 1980-12-23 | — | — | US | disclosed |