Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387455 | 0.84 | TBXAS1 (1.00) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11493719 | 0.84 | TBXAS1 (0.72) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11494396 | 0.84 | TBXAS1 (0.72) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11349273 | 0.84 | TBXAS1 (0.72) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11488027 | 0.83 | TBXAS1 (0.67) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11054251 | 0.83 | TBXAS1 (0.67) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9214699 | 0.80 | TBXAS1 (1.00) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8545405 | 0.79 | TBXAS1 (0.65) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6945754 | 0.76 | HTR1A (0.79) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11491883 | 0.75 | CYP19A1 (0.61) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217357-A | Inhibition of thromboxane synthetase with 3-(imidazol-1-ylalkyl)indoles | PFIZER INC. (US) | 1980-08-12 | — | — | US | disclosed |