Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.46 |
| ▸ | FNTB | P49356 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489566 | 0.90 | HTT (0.47) | FNTAFNTBHTTFFAR1LTA4H | |
| SCHEMBL11489493 | 0.88 | HTT (0.49) | HTTFFAR1MTNR1AMTNR1BRAB9A | |
| SCHEMBL11494345 | 0.86 | LTA4H (0.49) | FNTAFNTBFFAR1LTA4HMMP1 | |
| SCHEMBL11494183 | 0.85 | CNR1 (0.46) | FNTAFNTBFFAR1LTA4HEPHX2 | |
| SCHEMBL11493561 | 0.79 | FFAR1 (0.39) | FNTAFNTBFFAR1MAPTUTS2R | |
| SCHEMBL11489266 | 0.79 | SLC6A4 (0.52) | FNTAFNTBFFAR1UTS2R | |
| SCHEMBL11489538 | 0.78 | FFAR1 (0.39) | FNTAFNTBFFAR1MAPTUTS2R | |
| SCHEMBL11489610 | 0.77 | MEN1 (0.40) | FNTAFNTBFFAR1RAB9AALDH1A1 | |
| SCHEMBL11492434 | 0.77 | HTT (0.50) | HTTACACAMTNR1AMTNR1BRAB9A | |
| SCHEMBL26262860 | 0.77 | MTNR1A (0.57) | EPHX2MTNR1AMTNR1BCNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |