Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494345 | 0.88 | LTA4H (0.49) | CNR1FFAR1FNTAFNTBUTS2R | |
| SCHEMBL11489195 | 0.87 | CNR1 (0.49) | CNR1DRD2DRD4UTS2RCYP2D6 | |
| SCHEMBL11489286 | 0.85 | FNTA (0.46) | CNR1FFAR1FNTAFNTBUTS2R | |
| SCHEMBL11489566 | 0.83 | HTT (0.47) | FFAR1FNTAFNTBACACAMMP1 | |
| SCHEMBL11489266 | 0.80 | SLC6A4 (0.52) | FFAR1FNTAFNTBUTS2R | |
| SCHEMBL11489610 | 0.79 | MEN1 (0.40) | FFAR1FNTAFNTBUTS2RCYP1A2 | |
| SCHEMBL11493561 | 0.77 | FFAR1 (0.39) | FFAR1DRD2DRD4FNTAFNTB | |
| SCHEMBL11507121 | 0.76 | FFAR1 (0.46) | FFAR1FNTAFNTBUTS2RLTA4H | |
| SCHEMBL11606085 | 0.76 | FFAR1 (0.39) | CNR1FFAR1FNTAFNTBUTS2R | |
| SCHEMBL11496048 | 0.76 | FFAR1 (0.39) | FFAR1FNTAFNTBUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |