Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802432 | 0.81 | KDM4E (0.50) | L3MBTL1MEN1KMT2ASIGMAR1LMNA | |
| SCHEMBL8325936 | 0.79 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2ASIGMAR1DDB1 | |
| SCHEMBL596252 | 0.79 | L3MBTL1 (0.96) | L3MBTL1MEN1KMT2ADDB1CRBN | |
| SCHEMBL13946682 | 0.79 | SMN1; SMN2 (0.58) | L3MBTL1MEN1KMT2ALMNAPOLB | |
| SCHEMBL22743960 | 0.79 | GAA (0.54) | SIGMAR1LMNAHTTHRH3TSHR | |
| SCHEMBL7269112 | 0.78 | L3MBTL1 (1.00) | L3MBTL1MEN1KMT2ADDB1CRBN | |
| SCHEMBL9212361 | 0.78 | L3MBTL1 (1.00) | L3MBTL1MEN1KMT2ADDB1CRBN | |
| SCHEMBL1626076 | 0.78 | L3MBTL1 (1.00) | L3MBTL1MEN1KMT2ADDB1CRBN | |
| SCHEMBL28946777 | 0.78 | L3MBTL1 (0.65) | L3MBTL1MEN1KMT2ASIGMAR1DDB1 | |
| SCHEMBL610772 | 0.78 | L3MBTL1 (1.00) | L3MBTL1MEN1KMT2ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007067-A1 | Phenylpiperidine derivatives, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-01-23 | — | — | EP | disclosed |