Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paraben SCHEMBL11483686 | 0.93 | CA2 (0.57) | TSHRTP53ALDH1A1SRD5A2CA1 | |
| Benzoic Acid SCHEMBL8432319 | 0.92 | TSHR (0.54) | TSHRTP53ALDH1A1SRD5A2KMT2A | |
| Benzoic Acid SCHEMBL9563653 | 0.92 | TSHR (0.54) | TSHRTP53ALDH1A1SRD5A2KMT2A | |
| 4-Methylbenzoic Acid SCHEMBL11482547 | 0.91 | ALDH1A1 (0.59) | TSHRTP53ALDH1A1SRD5A2CA1 | |
| Isophthalic Acid SCHEMBL11490528 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA12CA6 | |
| SCHEMBL28446206 | 0.84 | KDM4E (0.47) | TSHRALDH1A1CA1CA2CA12 | |
| SCHEMBL31553167 | 0.84 | PKM (0.49) | TSHRTP53ALDH1A1SRD5A2SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL2687529 | 0.84 | TSHR (0.63) | TSHRTP53ALDH1A1SRD5A2CA1 | |
| Terephthalic Acid SCHEMBL11490240 | 0.84 | TSHR (0.63) | TSHRTP53ALDH1A1SRD5A2CA1 | |
| Terephthalic Acid SCHEMBL8506032 | 0.84 | TSHR (0.63) | TSHRTP53ALDH1A1SRD5A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631779-B | Polyol esters and their use in processing halogenated vinyl polymers | 济南金昌树新材料科技有限公司 | 2020-07-14 | — | — | CN | disclosed |
| US-4202806-A | HEAT STABILIZERS | KOEI CHEMICAL CO., LTD. (JP) | 1980-05-13 | — | — | US | disclosed |