Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490287 | 0.87 | EPHX1 (0.42) | KMT2AMEN1ATMPOLBCASR | |
| SCHEMBL7403326 | 0.81 | APAF1 (0.50) | KMT2AMEN1POLBCASRRAB9A | |
| SCHEMBL11491237 | 0.78 | CA12 (0.45) | KMT2AMEN1ATMRAB9ACYP1A2 | |
| SCHEMBL10332375 | 0.72 | MEN1 (0.41) | KMT2AMEN1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17445799 | 0.71 | POLB (0.41) | KMT2AMEN1POLBLMNAKDM4E | |
| SCHEMBL8262659 | 0.71 | MAOB (0.50) | POLBRAB9AHTTLMNAALDH1A1 | |
| SCHEMBL7148105 | 0.71 | MAOB (0.50) | POLBRAB9AHTTLMNAALDH1A1 | |
| SCHEMBL7150103 | 0.71 | MAOB (0.50) | POLBRAB9AHTTLMNAALDH1A1 | |
| SCHEMBL15572889 | 0.70 | KMT2A (0.55) | KMT2AMEN1ATMRAB9AKLK7 | |
| SCHEMBL17291665 | 0.70 | KMT2A (0.55) | KMT2AMEN1ATMRAB9AKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |