Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490287 | 0.79 | EPHX1 (0.42) | ATMKMT2AMEN1CYP2C9RAB9A | |
| SCHEMBL11490284 | 0.78 | KMT2A (0.41) | ATMKMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL30368057 | 0.76 | FOLH1 (0.44) | FOLH1ATMKMT2ANAALAD2MAPT | |
| SCHEMBL11039517 | 0.74 | FOLH1 (0.51) | FOLH1ATMKMT2ANAALAD2MAPT | |
| SCHEMBL15661797 | 0.73 | FOLH1 (0.50) | CA2FOLH1ATMKMT2ANAALAD2 | |
| SCHEMBL2338313 | 0.73 | FOLH1 (0.50) | CA2FOLH1ATMKMT2ANAALAD2 | |
| SCHEMBL7403326 | 0.72 | APAF1 (0.50) | KMT2AALDH1A1MEN1CYP1A2ALOX15 | |
| SCHEMBL6129097 | 0.71 | FOLH1 (0.47) | CA12CA1CA2TYRCA7 | |
| SCHEMBL5995942 | 0.71 | FOLH1 (0.47) | CA12CA1CA2TYRCA7 | |
| SCHEMBL5904162 | 0.71 | FOLH1 (0.47) | CA12CA1CA2TYRCA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226864-A | BACTERICIDES, ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |