Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490284 | 0.87 | KMT2A (0.41) | KMT2AMEN1ATMCASRPOLB | |
| SCHEMBL7403326 | 0.82 | APAF1 (0.50) | KMT2AMEN1CASRPOLBRAB9A | |
| SCHEMBL11491237 | 0.79 | CA12 (0.45) | KMT2AMEN1ATMRAB9ACYP2C9 | |
| SCHEMBL24495090 | 0.74 | MTNR1A (0.50) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL4196020 | 0.73 | SMN1; SMN2 (0.43) | EPHX1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL10332377 | 0.73 | EPHX1 (0.46) | EPHX1SMN1; SMN2CYP3A4CYP2C9PDGFRA | |
| SCHEMBL8307199 | 0.72 | TSHR (0.43) | KMT2AATMSYKPOLBSMN1; SMN2 | |
| SCHEMBL17445799 | 0.72 | POLB (0.41) | KMT2AMEN1POLBGPR88 | |
| SCHEMBL17291665 | 0.71 | KMT2A (0.55) | KMT2AMEN1ATMRAB9AKLK7 | |
| SCHEMBL17305914 | 0.71 | KMT2A (0.55) | KMT2AMEN1ATMRAB9AKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |