Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439247 | 1.00 | LMNA (0.50) | LMNAMAPK1KAT6ABLMNPSR1 | |
| SCHEMBL11488242 | 0.90 | LMNA (0.47) | LMNAMAPK1CYSLTR2CYSLTR1PPARG | |
| SCHEMBL11451021 | 0.90 | LMNA (0.47) | LMNAMAPK1CYSLTR2CYSLTR1PPARG | |
| SCHEMBL2552459 | 0.86 | LMNA (0.53) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL2552458 | 0.86 | LMNA (0.53) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL2060445 | 0.83 | PTGS2 (0.54) | LMNAMAPK1BLMTSHRPTGS2 | |
| SCHEMBL19387547 | 0.82 | LMNA (0.48) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL27910194 | 0.80 | CNR1 (0.42) | LMNAPGK1PGK2 | |
| SCHEMBL9015267 | 0.80 | LMNA (0.50) | LMNAMAPK1BLMTSHRPTGS2 | |
| SCHEMBL11477890 | 0.79 | LMNA (0.52) | LMNAMAPK1PTGS2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |