Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191769 | 0.88 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| SCHEMBL11416327 | 0.85 | GABRA1 (0.40) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| Carbimide SCHEMBL29047475 | 0.83 | GABRA1 (0.46) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| SCHEMBL24228574 | 0.83 | GABRA1 (0.39) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| SCHEMBL374209 | 0.82 | GABRA1 (0.56) | GABRA1GABRB2CYP3A4TSHRCA1 | |
| SCHEMBL112144 | 0.81 | CYP3A4 (0.52) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| SCHEMBL1019702 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| SCHEMBL9623520 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4LMNAGABRG2 | |
| SCHEMBL3440189 | 0.80 | CYP3A4 (0.50) | GABRA1GABRB2CYP3A4TRPA1 | |
| SCHEMBL1456958 | 0.79 | GABRA1 (0.70) | GABRA1GABRB2CYP3A4LMNAGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304446-B | Derivatization method of optically active phenylacetylene compound | UNIV HARBIN ENG | 2015-02-25 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-20250223263-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NodThera Limited (GB) | 2025-07-10 | — | — | US | disclosed |
| US-12247011-B2 | Selective inhibitors of NLRP3 inflammasome | NodThera Limited (GB) | 2025-03-11 | — | — | US | disclosed |
| CN-118930990-A | Preparation process of flexible plastic sports ground material | 道一高分子聚合物(宁波)有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-111356680-B | Selective inhibitors of NLRP3 inflammasome | 诺瑟拉有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-3661921-B1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NODTHERA LTD (GB) | 2023-10-18 | — | — | EP | disclosed |
| EP-3661921-B1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NODTHERA LTD (GB) | 2023-10-18 | — | — | EP | disclosed |
| US-11773312-B2 | Breaker additives for extended delay in removal of oil-based filter cakes | HALLIBURTON ENERGY SERVICES, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220220358-A1 | Breaker Additives For Extended Delay In Removal Of Oil-Based Filter Cakes | HALLIBURTON ENERGY SERVICES, INC. (US) | 2022-07-14 | — | — | US | disclosed |
| CN-114231163-A | Polyurethane organic-inorganic composite material and preparation method and application thereof | 武汉工程大学 | 2022-03-25 | — | — | CN | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998032733-A1 | SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY | PFIZER INC. (US) | 1998-07-30 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| EP-0816309-A1 | Scavenger assisted combinatorial process for preparing libraries of urea and thiourea compounds | ELI LILLY AND COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| CN-1047859-A | Benzo cycloalkane derivatives and preparation method thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-12-19 | — | — | CN | disclosed |
| EP-0217787-A4 | AMIDINOUREA PROCESS AND PHARMACEUTICAL COMPOSITION. | RORER INTERNAT OVERSEAS INC (US) | 1988-07-21 | — | — | EP | disclosed |
| EP-0217787-A1 | AMIDINOUREA PROCESS AND PHARMACEUTICAL COMPOSITION | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1987-04-15 | — | — | EP | disclosed |
| WO-1986004935-A1 | AMIDINOUREA PROCESS AND PHARMACEUTICAL COMPOSITION | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1986-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247011-B2 | Selective inhibitors of NLRP3 inflammasome | NLRP3, NOD1, NLRP1 | GABRA1 2922/4885GABRB2 2882/4885CYP3A4 2832/4885 |
| US-20250223263-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, NLRP1 | GABRA1 2922/4885GABRB2 2882/4885CYP3A4 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.