Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19597624 | 0.80 | LMNA (0.61) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL1672481 | 0.79 | LMNA (0.66) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL17153804 | 0.78 | MAPT (0.59) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL19086928 | 0.76 | LMNA (0.61) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL353166 | 0.76 | LMNA (0.61) | LMNACYP1A2MAPTTHRBALOX15 | |
| Zoxazolamine SCHEMBL251567 | 0.76 | LMNA (1.00) | LMNACYP1A2MAPTTHRBALOX15 | |
| Zoxazolamine SCHEMBL10891033 | 0.76 | LMNA (1.00) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL9304987 | 0.76 | LMNA (0.61) | LMNACYP1A2MAPTTHRBALOX15 | |
| Chlorzoxazone SCHEMBL35177 | 0.76 | KDM4E (0.70) | LMNACYP1A2MAPTTHRBALOX15 | |
| SCHEMBL31507497 | 0.76 | LMNA (0.61) | LMNACYP1A2MAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234578-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |