Sugi Predict

Sugi Predict / Compounds / SCHEMBL353166

SCHEMBL353166

SCHEMBL353166

Cc1nc2cc(Cl)ccc2o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.61
▸ CYP1A2 P05177 2/20 0.61
▸ THRB P10828 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ ALOX15 P16050 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ KDM4E B2RXH2 6/20 0.60
▸ SMN1; SMN2 Q16637 5/20 0.60
▸ ALDH1A1 P00352 3/20 0.60
▸ HPGD P15428 2/20 0.60
▸ NFKB1 P19838 1/20 0.60
▸ NFKB2 Q00653 1/20 0.60
▸ RELA Q04206 1/20 0.60
▸ NPC1 O15118 6/20 0.57
▸ RAB9A P51151 6/20 0.57
▸ CASP3 P42574 3/20 0.57
▸ SENP7 Q9BQF6 3/20 0.57
▸ SENP6 Q9GZR1 2/20 0.57
▸ SENP8 Q96LD8 1/20 0.57
▸ L3MBTL1 Q9Y468 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31507497 1.00 LMNA (0.61) LMNACYP1A2THRBMAPTALOX15
SCHEMBL2056293 0.84 PIK3CG (0.61) LMNACYP1A2THRBMAPTALOX15
SCHEMBL8870228 0.81 FBP1 (0.60) LMNACYP1A2THRBMAPTALOX15
SCHEMBL29442076 0.79 NPC1 (0.61) MAPTKDM4ESMN1; SMN2ALDH1A1HPGD
SCHEMBL1672481 0.79 LMNA (0.66) LMNACYP1A2THRBMAPTALOX15
SCHEMBL9105844 0.79 NPC1 (0.61) MAPTKDM4ESMN1; SMN2ALDH1A1HPGD
SCHEMBL903255 0.79 NPC1 (0.61) MAPTKDM4ESMN1; SMN2ALDH1A1HPGD
SCHEMBL13528421 0.79 L3MBTL1 (0.82) LMNAMAPTKDM4ESMN1; SMN2ALDH1A1
Iodide SCHEMBL8417295 0.78 NPC1 (0.59) MAPTKDM4ESMN1; SMN2ALDH1A1HPGD
Chlorzoxazone SCHEMBL27696905 0.77 KDM4E (0.66) LMNACYP1A2THRBMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715977-A Preparation method of hemicyanine dye 沈阳师范大学 2023-09-08 — — CN claimed
CN-110950764-A Method for synthesizing 2-amino-4-chloro-5 nitrophenol in microchannel reactor 沈阳感光化工研究院有限公司 2020-04-03 — — CN claimed
CN-106916369-A Preparation method of high-crystalline polypropylene special material 中国石油天然气股份有限公司 2017-07-04 — — CN claimed
CN-103571037-A Preparation method of polypropylene resin PETROCHINA CO LTD 2014-02-12 — — CN claimed
CN-101638500-B Composite additive for random copolymerization polypropylene pipe PETROCHINA CO LTD 2011-05-25 — — CN claimed
CN-101638500-A Composite additive for random copolymerization polypropylene pipe PETROCHINA CO LTD 2010-02-03 — — CN claimed
US-20250282785-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2025-09-11 — — US disclosed
CN-120082223-A Preparation method of cyanine dye Cy3 沈阳师范大学 2025-06-03 — — CN disclosed
EP-4522608-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN Pharmaceutica NV (BE) 2025-03-19 — — EP disclosed
CN-114981360-B Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2024-09-10 — — CN disclosed
US-20240025879-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF EDGEWISE THERAPEUTICS, INC. 2024-01-25 — — US disclosed
WO-2023217906-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2023-11-16 — — WO disclosed
US-20230321091-A1 SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES EDGEWISE THERAPEUTICS, INC. 2023-10-12 — — US disclosed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 — — US disclosed
US-4861897-A 2-Aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles ORTHO PHARMACEUTICAL CORPORATION (US) 1989-08-29 — — US disclosed
EP-0318084-A2 Benzoheterazoles MERCK FROSST CANADA INC. (CA) 1989-05-31 — — EP disclosed
US-4828973-A DIRECT POSITIVES WITH REVERSAL PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-09 — — US disclosed
US-4740455-A Heat developable light-sensitive material containing polymethine FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 — — US disclosed
US-4539408-A Process for the preparation of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-09-03 — — US disclosed
US-4074046-A REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE AMERICAN CYANAMID COMPANY (US) 1978-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321091-A1 SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES IL6, MUSK, SMN1; SMN2 LMNA 340/4885CYP1A2 1703/4885THRB 3010/4885
US-20250282785-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE NFKBIA, IKBKG, IKBKB LMNA 2373/4885CYP1A2 4351/4885THRB 2006/4885
US-20240025879-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF IL6, IL1B, IL1A LMNA 439/4885CYP1A2 1767/4885THRB 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.