Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 13/20 | 0.78 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.73 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23407733 | 0.90 | PDE7A (0.68) | PDE7APDE7BPDE4BPDE4DMEN1 | |
| SCHEMBL8308859 | 0.87 | PDE7A (1.00) | PDE7APDE7BPDE4BPDE4DHSD17B10 | |
| SCHEMBL7605579 | 0.87 | PDE7A (0.67) | PDE7APDE7BPDE4BPDE4DHSD17B10 | |
| SCHEMBL27581742 | 0.86 | PDE7A (0.75) | PDE7APDE7BPDE4BPDE4DHSD17B10 | |
| SCHEMBL27561251 | 0.86 | TXNRD1 (0.70) | PDE7APDE7BPDE4BPDE4DTXNRD1 | |
| SCHEMBL7608814 | 0.86 | PDE7A (0.71) | PDE7APDE7BPDE4BPDE4DHSD17B10 | |
| SCHEMBL715750 | 0.84 | PDE7A (1.00) | PDE7APDE7BPDE4BPDE4DHSD17B10 | |
| SCHEMBL28325601 | 0.84 | PDE7A (0.57) | PDE7APDE7BPDE4BPDE4DMEN1 | |
| SCHEMBL3029788 | 0.84 | PDE7A (0.68) | PDE7APDE7BPDE4BPDE4DHSD17B10 | |
| SCHEMBL10924255 | 0.83 | PDE7A (0.76) | PDE7APDE7BPDE4BPDE4DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780202-B1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-7880006-B2 | 4-Acetoxy-5-chloro-6-(4-chlorophenoxy)-2,3-dimethyl-quinoline, used as agricultural and horticultural insecticides | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| EP-1780202-A1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA KAISHA LTD. (JP) | 2007-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | DDT, ACHE, NQO1 | PDE7A 198/4885PDE7B 116/4885PDE4B 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.