Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606085 | 0.82 | FFAR1 (0.39) | FFAR1HTR2ASLC6A4KMT2ACYP2D6 | |
| SCHEMBL11494016 | 0.80 | XIAP (0.50) | XIAPFFAR1KMT2AEZH2MAPK14 | |
| SCHEMBL11488201 | 0.80 | XIAP (0.48) | XIAPFFAR1HTR2ASLC6A4 | |
| SCHEMBL11494083 | 0.80 | SLC6A4 (0.56) | HTR2ASLC6A4KMT2AADRB2ADRB1 | |
| SCHEMBL11427982 | 0.78 | XIAP (0.48) | XIAPFFAR1HTR2ASLC6A4CASP1 | |
| SCHEMBL11487251 | 0.77 | SLC6A4 (0.46) | XIAPFFAR1HTR2ASLC6A4 | |
| SCHEMBL5018840 | 0.75 | XIAP (0.54) | XIAPFFAR1HTR2ASLC6A4CASP1 | |
| SCHEMBL22957833 | 0.75 | RIPK1 (0.58) | CASRHTR2ASLC6A4KMT2ACYP2D6 | |
| SCHEMBL11489456 | 0.75 | LPAR1 (0.42) | XIAPFFAR1HTR2ASLC6A4 | |
| SCHEMBL11494143 | 0.73 | TSHR (0.49) | KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |