Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489472 | 0.86 | AKT1 (0.44) | NPSR1UTS2RKMT2A | |
| SCHEMBL11493561 | 0.84 | FFAR1 (0.39) | FFAR1GAASLC6A4UTS2RMAOA | |
| SCHEMBL11489266 | 0.83 | SLC6A4 (0.52) | FFAR1GAASLC6A4UTS2RMAOA | |
| SCHEMBL11494080 | 0.82 | XIAP (0.43) | FFAR1SLC6A4HTR2AKMT2ACYP2D6 | |
| SCHEMBL11489610 | 0.82 | MEN1 (0.40) | FFAR1GAASLC6A4UTS2RMAOA | |
| SCHEMBL11494083 | 0.80 | SLC6A4 (0.56) | SLC6A4HTR2AKMT2ACYP2D6 | |
| SCHEMBL11496048 | 0.79 | FFAR1 (0.39) | FFAR1GAASLC6A4UTS2RMAOA | |
| SCHEMBL11489538 | 0.79 | FFAR1 (0.39) | FFAR1GAASLC6A4UTS2RMAOA | |
| SCHEMBL11495474 | 0.78 | MEN1 (0.41) | FFAR1GAASLC6A4NPSR1UTS2R | |
| SCHEMBL11496101 | 0.77 | KMT2A (0.42) | FFAR1GAASLC6A4KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |