Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494115 | 1.00 | CTSS (0.53) | CTSSCTSKFNTAFNTBBACE1 | |
| SCHEMBL12835706 | 0.90 | CTSS (0.56) | CTSSCTSKFNTAFNTBBACE1 | |
| SCHEMBL29558421 | 0.90 | CTSS (0.56) | CTSSCTSKFNTAFNTBBACE1 | |
| SCHEMBL29475211 | 0.88 | CTSK (0.54) | CTSSCTSKFNTAFNTBBACE1 | |
| SCHEMBL10788830 | 0.87 | REN (0.47) | CTSSCTSKKMT2AATMCA2 | |
| SCHEMBL28501207 | 0.87 | REN (0.47) | CTSSCTSKKMT2AATMCA2 | |
| SCHEMBL28501209 | 0.87 | REN (0.47) | CTSSCTSKKMT2AATMCA2 | |
| SCHEMBL7536416 | 0.87 | CTSS (0.49) | CTSSCTSKREN | |
| SCHEMBL7536423 | 0.87 | CTSS (0.49) | CTSSCTSKREN | |
| SCHEMBL1486176 | 0.86 | PPARA (0.47) | CTSSCTSKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669106-B2 | Conjugate of monomethyl auristatin F and trastuzumab and its use for the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2017-06-06 | — | — | US | disclosed |
| EP-0014984-A1 | Glucosamine-peptide derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-09-03 | — | — | EP | disclosed |