Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487644 | 0.90 | LMNA (0.49) | KMT2AALDH1A1KDM4EMEN1SLC6A4 | |
| SCHEMBL11494400 | 0.90 | CHRM4 (0.48) | KMT2AALDH1A1KDM4EMEN1SLC6A4 | |
| SCHEMBL11489482 | 0.89 | CYP2D6 (0.50) | KMT2AALDH1A1KDM4EMEN1TDP1 | |
| SCHEMBL11487383 | 0.88 | CYP2D6 (0.52) | KMT2AALDH1A1KDM4EMEN1TDP1 | |
| SCHEMBL11489627 | 0.87 | CHRM3 (0.46) | KMT2AALDH1A1KDM4EMEN1PKM | |
| SCHEMBL11492203 | 0.86 | CHRM2 (0.47) | KMT2AALDH1A1KDM4EMEN1TDP1 | |
| SCHEMBL11486718 | 0.85 | KDM4E (0.48) | KMT2AALDH1A1KDM4EMEN1RAB9A | |
| SCHEMBL11488616 | 0.84 | SLC6A4 (0.40) | KMT2AALDH1A1KDM4EMEN1SLC6A4 | |
| SCHEMBL11489633 | 0.84 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4EMEN1MAPK1 | |
| SCHEMBL11495149 | 0.81 | SLC6A4 (0.55) | KMT2AALDH1A1MEN1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |