Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489610 | 0.87 | MEN1 (0.40) | MEN1KMT2AKDM4EALDH1A1FFAR1 | |
| SCHEMBL11489088 | 0.87 | MEN1 (0.44) | MEN1KMT2ANPSR1HTTHPGD | |
| SCHEMBL11493561 | 0.82 | FFAR1 (0.39) | MEN1KMT2AFFAR1GAAMAPT | |
| SCHEMBL11489266 | 0.82 | SLC6A4 (0.52) | FFAR1GAASLC6A4UTS2RFNTA | |
| SCHEMBL11489538 | 0.81 | FFAR1 (0.39) | MEN1KMT2AFFAR1GAAMAPT | |
| SCHEMBL27629258 | 0.80 | FFAR1 (0.43) | FFAR1GAAMAPTSLC6A4UTS2R | |
| SCHEMBL11496101 | 0.79 | KMT2A (0.42) | MEN1KMT2AFFAR1GAASMN1; SMN2 | |
| SCHEMBL11606085 | 0.78 | FFAR1 (0.39) | KMT2ANPSR1FFAR1GAASLC6A4 | |
| SCHEMBL11496048 | 0.78 | FFAR1 (0.39) | MEN1KMT2AFFAR1GAASLC6A4 | |
| SCHEMBL11489286 | 0.77 | FNTA (0.46) | HTTALDH1A1FFAR1MAPTUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |