Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495474 | 0.87 | MEN1 (0.41) | MEN1KMT2ANPSR1HTTHPGD | |
| SCHEMBL11489474 | 0.85 | AKT1 (0.45) | AKT1KDM4EHTR1AADRB2HTR7 | |
| SCHEMBL11492769 | 0.84 | ALDH1A1 (0.38) | KMT2AHTTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL11488016 | 0.81 | AKT1 (0.41) | MEN1KMT2AAKT1KDM4EADRB2 | |
| SCHEMBL11496377 | 0.80 | SLC6A4 (0.45) | AKT1ADRB2SLC6A2HTR2ASLC6A4 | |
| SCHEMBL11603164 | 0.79 | AKT1 (0.40) | MEN1KMT2AAKT1SMN1; SMN2ADRB2 | |
| SCHEMBL22957649 | 0.78 | HTR1A (0.53) | MEN1KMT2ANPSR1HTTSMN1; SMN2 | |
| SCHEMBL25671392 | 0.77 | ADRB2 (0.46) | AKT1HPGDGAAALDH1A1ADRB2 | |
| SCHEMBL11489175 | 0.77 | SMN1; SMN2 (0.44) | MEN1KMT2AAKT1SMN1; SMN2DRD2 | |
| SCHEMBL11489472 | 0.76 | AKT1 (0.44) | KMT2ANPSR1AKT1HPGDADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |