Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591177 | 0.90 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL27927983 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10UTS2R | |
| SCHEMBL4771680 | 0.75 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10BDKRB1 | |
| SCHEMBL27910337 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10UTS2R | |
| SCHEMBL16726632 | 0.74 | CA12 (0.44) | KDM4EALDH1A1HPGDHSD17B10KDM6B | |
| SCHEMBL31368236 | 0.74 | CA12 (0.44) | KDM4EALDH1A1HPGDHSD17B10KDM6B | |
| SCHEMBL23857227 | 0.73 | L3MBTL1 (0.47) | KDM4EALDH1A1HPGDKDM6BKDM4C | |
| SCHEMBL12515865 | 0.73 | CA12 (0.47) | KDM4EALDH1A1HPGDHSD17B10KDM6B | |
| SCHEMBL30867527 | 0.73 | CA12 (0.47) | KDM4EALDH1A1HPGDHSD17B10KDM6B | |
| SCHEMBL30047213 | 0.73 | L3MBTL1 (0.47) | KDM4EALDH1A1HPGDKDM6BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |