Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149048 | 0.88 | ALDH1A1 (0.41) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL15184112 | 0.88 | ALDH1A1 (0.41) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL9642169 | 0.86 | CNR2 (0.43) | ALDH1A1KMT2AMEN1RAB9ARECQL | |
| SCHEMBL7715767 | 0.84 | CNR2 (0.41) | ALDH1A1KMT2AMEN1RAB9ARECQL | |
| SCHEMBL10967255 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21461267 | 0.79 | ALDH1A1 (0.32) | ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL10454497 | 0.76 | ALDH1A1 (0.41) | USP2ALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL11818302 | 0.75 | SMN1; SMN2 (0.47) | HTTHSD17B10TSHRALDH1A1KMT2A | |
| SCHEMBL7483292 | 0.74 | HTT (0.51) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL7480871 | 0.74 | HTT (0.51) | HTTHSD17B10USP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4193927-A | USED IN MANUFACTURE OF POLYMERS WHICH CAN BE CROSSLINKED BY LIGHT | CIBA-GEIGY CORPORATION (US) | 1980-03-18 | — | — | US | disclosed |
| US-4174326-A | Imidyl compounds | CIBA-GEIGY CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| US-4172836-A | Imidyl compounds | CIBA-GEIGY CORPORATION (US) | 1979-10-30 | — | — | US | disclosed |
| US-4107174-A | POLYMER MONOMERS | CIBA-GEIGY CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |