SCHEMBL10967255

SCHEMBL10967255

O=C1C2C=CCCC2C(=O)N1CO

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.31
CYP2D6 P10635 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15184112 0.87 ALDH1A1 (0.41) ALDH1A1ATM
SCHEMBL8149048 0.87 ALDH1A1 (0.41) ALDH1A1ATM
SCHEMBL11818302 0.82 SMN1; SMN2 (0.47) ALDH1A1
SCHEMBL11496751 0.82 HTT (0.43) ALDH1A1
SCHEMBL11829965 0.81 RAB9A (0.49) ALDH1A1
SCHEMBL21461267 0.80 ALDH1A1 (0.32) ALDH1A1ATM
SCHEMBL6256506 0.80
SCHEMBL9383280 0.79 MAOA (0.33)
SCHEMBL3847282 0.79 ALDH1A1 (0.44) ALDH1A1
SCHEMBL675969 0.78 TP53 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0105006-B1 ALLENIC CYCLOPROPANE CARBOXYLATES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-03-19 EP claimed
US-4515768-A STABILIZER AGAINST THERMAL DECOMPOSITION AIRWICK INDUSTRIES, INC. (US) 1985-05-07 US disclosed
US-4485252-A INSECTICIDES AND MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1984-11-27 US disclosed
EP-0037375-B1 INSECTICIDAL-VAPOURS EMITTING DEVICE Airwick AG (CH) 1984-05-23 EP disclosed
EP-0036385-B1 INSECTICIDAL VAPOUR-EMITTING COMPOSITIONS ON THE BASIS OF PYRETHRINOIDS Airwick AG (CH) 1984-05-02 EP disclosed
US-4439415-A PYRETHRINOID AND ABSORPTIVE SUBSTRATE AIRWICK INDUSTRIES, INC. (US) 1984-03-27 US disclosed
US-4344963-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed
US-4297366-A INSECTICIDES, MITICIDES, AND PARASITICIDES; VETERINARY MEDICINE BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
EP-0036385-A2 Insecticidal vapour-emitting compositions on the basis of pyrethrinoids Airwick AG (CH) 1981-09-23 EP disclosed
EP-0020954-A1 Fluoro-substituted oxyalkenyl-cyclopropane-carboxylic acid esters, process for their production, intermediates therefor, their production, insecticides and acaricides that contain the final products, their preparation and use BAYER AG (DE) 1981-01-07 EP disclosed
EP-0019787-A2 2-Phenylalken-1-yl-cyclopropane-carboxylic acid esters, process for their preparation and their use as insecticides and acaricides; intermediates in their preparation BAYER AG (DE) 1980-12-10 EP disclosed
US-4077971-A ULTRAVIOLET ABSORBERS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-07 US disclosed