SCHEMBL1149765

SCHEMBL1149765

CCCCCn1c2ccccc2c2cc(N)ccc21

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.69
MEN1 O00255 1/20 0.69
ALDH1A1 P00352 1/20 0.69
MAPT P10636 1/20 0.69
HPGD P15428 1/20 0.69
MAPK1 P28482 1/20 0.69
HTT P42858 1/20 0.69
HBB P68871 1/20 0.69
KMT2A Q03164 1/20 0.69
HSD17B10 Q99714 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
CNR2 P34972 14/20 0.60
SIGMAR1 Q99720 1/20 0.60
NPC1 O15118 1/20 0.54
CNR1 P21554 1/20 0.54
PGR P06401 1/20 0.51
RORA P35398 1/20 0.51
RORC P51449 1/20 0.51
RORB Q92753 1/20 0.51
PSEN1 P49768 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9397292 0.98 KDM4E (0.68) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL5012113 0.98 KDM4E (0.68) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL8124194 0.98 KDM4E (0.68) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL10945941 0.95 ALDH1A1 (0.71) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL31739343 0.95 ALDH1A1 (0.71) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL11340644 0.94 KDM4E (0.76) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL30884614 0.91 KDM4E (0.54) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL29208327 0.91 KDM4E (0.54) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL11757062 0.89 KDM4E (0.76) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL19974241 0.87 ALDH1A1 (0.57) KDM4EMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180309080-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-10-25 US claimed
US-20140034932-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-06 US claimed
CN-108321303-B Light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2021-03-09 CN disclosed
CN-108539032-B Light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-02-21 CN disclosed
US-20180309080-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-10-25 US disclosed
US-20140034932-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-06 US disclosed
US-8207214-B2 3-aminocarbazole compounds, pharmaceutical composition containing the same and method for the preparation thereof AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2012-06-26 US disclosed
US-20110046197-A1 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF AZIENDE CHIMICHE RIUNITE ANGELINI FRANCE (IT) 2011-02-24 US disclosed
US-7879900-B2 Antiinflammatory agents; antitumor agents; Alzheimer's disease;atherosclerosis AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2011-02-01 US disclosed
EP-1910288-B1 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF ACRAF (IT) 2010-06-23 EP disclosed
US-20080207727-A1 3-Aminocarbazole Compounds, Pharmaceutical Composition Containing the Same and Method for the Preparation Thereof AZIENDE CHIMICHE RIUNTE ANGELINI FRANCE (IT) 2008-08-28 US disclosed
EP-1910288-A1 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 2008-04-16 EP disclosed
WO-2007014687-A1 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207727-A1 3-Aminocarbazole Compounds, Pharmaceutical Composition Containing the Same and Method for the Preparation Thereof CYP2C19, CYP2C9, CYP3A43 KDM4E 1007/4885MEN1 1522/4885ALDH1A1 1131/4885
US-20110046197-A1 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF IL17A, APC, IL33 KDM4E 3434/4885MEN1 2803/4885ALDH1A1 1620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.