SCHEMBL11498917

SCHEMBL11498917

CC(C)(C)C(=O)COc1ccccc1N=Nc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
HTT P42858 1/20 0.54
MBTPS1 Q14703 2/20 0.50
PPARA Q07869 5/20 0.44
VDR P11473 1/20 0.43
ADRB2 P07550 1/20 0.41
PPARG P37231 4/20 0.41
PPARD Q03181 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
GLA P06280 1/20 0.41
KMT2A Q03164 2/20 0.40
HSP90AA1 P07900 1/20 0.40
AR P10275 1/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11498916 1.00 ALDH1A1 (0.54) ALDH1A1HTTMBTPS1PPARAVDR
SCHEMBL27568539 0.76 ALDH1A1 (0.46) ALDH1A1HTTMBTPS1ADRB2L3MBTL1
SCHEMBL20059975 0.74 ALDH1A1 (0.62) ALDH1A1HTTVDRL3MBTL1SMN1; SMN2
SCHEMBL5146714 0.73 PPARA (0.41) ALDH1A1HTTMBTPS1PPARAPPARG
SCHEMBL528862 0.73 LMNA (0.45) ALDH1A1HTTMBTPS1PPARAADRB2
SCHEMBL29383903 0.73 PPARA (0.52) ALDH1A1HTTPPARAPPARGPPARD
SCHEMBL3292333 0.73 PPARA (0.41) ALDH1A1HTTMBTPS1PPARAPPARG
SCHEMBL111612 0.73 PPARA (0.52) ALDH1A1HTTPPARAPPARGPPARD
SCHEMBL3295384 0.73 PPARA (0.41) ALDH1A1HTTMBTPS1PPARAPPARG
SCHEMBL3295387 0.73 PPARA (0.41) ALDH1A1HTTMBTPS1PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4199503-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1980-04-22 US disclosed
EP-0001571-A1 Phenylazophenyloxy-triazolyl derivatives and fungicides containing them BASF Aktiengesellschaft (DE) 1979-05-02 EP disclosed