SCHEMBL114996

SCHEMBL114996

CC(C)(CO)NCC(O)CNC(C)(C)CO

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.43
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11751768 0.90 PKM (0.41) PKM
SCHEMBL9647341 0.88 PKM (0.40) PKM
SCHEMBL3364056 0.86 PKM (0.39) PKM
SCHEMBL21787651 0.85 PKM (0.37) PKM
SCHEMBL12927514 0.84 PKM (0.36) PKMHTT
SCHEMBL1980860 0.83 PKM (0.38) PKM
SCHEMBL9647365 0.82 TDP1 (0.36) PKMHTT
SCHEMBL50906 0.80 PKM (0.39) PKM
SCHEMBL7117040 0.79 PKM (0.33) PKMHTT
SCHEMBL15279114 0.79 ADRB3 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424833-B1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES ANGUS CHEMICAL (US) 2015-07-29 EP claimed
US-8877979-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-04 US claimed
US-8790456-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies ANGUS CHEMICAL COMPANY 2014-07-29 US claimed
US-20140187820-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US claimed
US-20140187678-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US claimed
US-8702859-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-22 US claimed
US-20140031470-A1 DIAMINO ALCOHOL AND STRONG BASE NEUTRALIZERS FOR LOW VOC COATING COMPOSITIONS ANGUS CHEMICAL COMPANY 2014-01-30 US claimed
EP-2627720-A1 DIAMINO ALCOHOLS AND STRONG BASE AS NEUTRALIZERS FOR LOW VOC COATING COMPOSITIONS Dow Global Technologies LLC (US) 2013-08-21 EP claimed
EP-2450410-B1 Hase-thickened composition ROHM & HAAS (US) 2013-07-03 EP claimed
WO-2012087264-A1 DIAMINO ALCOHOLS AND STRONG BASE AS NEUTRALIZERS FOR LOW VOC COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO claimed
US-20120115999-A1 HASE-THICKENED COMPOSITION ANGUS CHEMICAL COMPANY 2012-05-10 US claimed
EP-2450410-A1 Hase-thickened composition Rohm and Haas Company (US) 2012-05-09 EP claimed
EP-2424833-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES Dow Global Technologies LLC (US) 2012-03-07 EP claimed
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ADVANCION CORPORATION 2012-02-09 US claimed
WO-2010126962-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-04 WO claimed
US-9115288-B2 Hase-thickened composition ROHM AND HAAS COMPANY (US) 2015-08-25 US disclosed
US-9115288-B2 Hase-thickened composition ROHM AND HAAS COMPANY (US) 2015-08-25 US disclosed
US-20100190993-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2010-07-29 US disclosed
US-20100099868-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2010-04-22 US disclosed
US-20090264651-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264651-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP PKM 111/4885HTT 2402/4885
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES AOC1, DAO, DDO PKM 3654/4885HTT 1623/4885
US-20100099868-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP PKM 111/4885HTT 2402/4885
US-20100190993-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP PKM 111/4885HTT 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.