Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500735 | 1.00 | GLO1 (0.56) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL6666853 | 0.95 | ALDH1A1 (0.53) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL11327350 | 0.92 | GLO1 (0.58) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL11327355 | 0.92 | GLO1 (0.58) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL3629745 | 0.87 | GLO1 (0.61) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL1613935 | 0.87 | GLO1 (0.61) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL3063302 | 0.87 | GLO1 (0.61) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL6367735 | 0.84 | ALOX5 (0.47) | ALDH1A1KMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL7814477 | 0.83 | GLO1 (0.48) | GLO1ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL7814475 | 0.83 | GLO1 (0.48) | GLO1ALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182897-A | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | TORII & CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |