Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341114 | 0.75 | ALOX15 (0.50) | HPGDKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL707494 | 0.75 | KDM4E (0.44) | HPGDMMP1MMP2MMP9MMP12 | |
| SCHEMBL724289 | 0.74 | GSK3B (0.40) | HPGDMMP1MMP2MMP9MMP12 | |
| SCHEMBL11008232 | 0.74 | KMT2A (0.39) | HPGDMMP1MMP2MMP9MMP12 | |
| SCHEMBL891160 | 0.73 | MMP1 (0.44) | HPGDMMP1MMP2MMP9MMP12 | |
| Potassium Ion SCHEMBL11800653 | 0.73 | HPGD (0.37) | HPGDMMP1MMP2MMP9MMP12 | |
| SCHEMBL8814468 | 0.71 | KMT2A (0.51) | HPGDRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11431451 | 0.70 | KMT2A (0.40) | HPGDRAB9ANPC1KMT2APOLB | |
| SCHEMBL3722741 | 0.70 | TDP1 (0.32) | — | |
| SCHEMBL5759533 | 0.69 | L3MBTL1 (0.39) | HPGDMMP1MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012072-A2 | Beta-lactones derived from 2-hydroxycyclopentane carboxylic acid, process for their preparation and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-06-11 | — | — | EP | disclosed |